Could it be an bigger underlying issue with your storage device or system (please see here)? Or a glitch in the downloading? Did you extract the zip to a folder before running it?
Try (re)downloading, unzipping, and running the portable non-installer version to see if it works. Make sure the .NET framework 4.7.1 is installed (should be already installed, but you can try downloading/installing it again here).
If it is still happening or you need further assistance, then please send me all info that you think could be helpful, including what exactly you have tried, screenshots of the error message, anything peculiar with your system setup, etc.