I like the usage of the theme. I didn't think of anything besides spiderwebs lol. It took me a second to realize the enemies parody Microsoft programs hahaha.
GradientOGames already brought up the pixel art mismatch so I won't rehash.
It did start a tad bit difficult early, but I got the hang of it after a few tries, so all good.
Regarding the inputs, hitting the keys for the numbers was a bit difficult, but not impossible so that was ok. Apart from that, I did have a slight issue with having to click LMB constantly. Maybe allowing the player to hold down and auto fire in time with the cooldowns might feel a bit more comfortable, while also having the existing option.
Otherwise, it was fun to play :)