TOTDC 2 will use Ren'py. As much as I might like RAGS, not only it's getting more difficult to run on modern systems, it has a very narrow design scope, some bugs and a number of quirks which make it hard to develop for it.
People will be able to continue their playthrough from TOTDC 1, though, I have since added a way to export the data from RAGS to Ren'py (it's a bit crude, but it works). You'd need to play the most recent update to TOTDC 1, if you are interested in that.