Well damn that's quite the improvement from last time.
The new graphics look great, especially the main character animations. Those slime enemies look unfitting though and the mixels annoy the shit out of me.
Gameplay feels much improved and I'm glad you seem to have dropped some of the odd mechanics like the pets or whatever they were called.
Effects like screen shake and hitstop seem a bit heavy for my taste but they don't impact the gameplay in a detrimental way as far as I'm concerned.
I never used subweapons because I found them too annoying to use compared to just shooting enemies.
As Qwott has noted I very quickly figured out you can really just skip past most things and not die. You need some kind of mechanic to make the player actually engage enemies.