For the hpc version for android not running, have you thought about making two files one for the apk and a separate for assets (that would need to be installed manually)?
Viewing post in Heavenly Peaks Cultivation comments
Ren'py packages the files , the bulk of file size comes from visual assets. The only real way to lower the file size at this point is to decrease the # of images placed into the game. I've already condensed them as much as possible without sacrificing visuals. There's not much I can do at this point and the game will only grow in size with development as well.