Thanks! I'll look into it.
I was able to make one for Menherafflesia, though it seems this game is too old to TPatch.
Glad it worked for the newer games, at least.
Also for anyone who might find it helpful, here's another way to extract the game files: when you run the EXE, the resources are unpacked into your Temp directory into the folder "nw8_16875". (EDIT: to clarify, "nw8_16875" is the temp folder for this specific game, but other Tyrano games follow the same pattern of nw[number]_[bunch of numbers].) Make a copy of that somewhere else and then overwrite the patched files.
You can then run the game in a web browser on various platforms, as I outline in this comment. That's how I used to run Tyranobuilder games in Linux until I learned that the easier way to get them to run properly in Wine is just to delete libGLESv2.dll for some reason.