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Thanks for playing and thanks for the feedback. 
Inventory issue was caused by my lack of experience with Godot and how it determines what resources should be included.
Explicitly load a specific file? yep, we'll include that.
Load all resources in a particular folder? Nope not in... 
I actually had it resolved within a few minutes of the submission deadline.

If you don't mind taking the time sharing... which interactions caused a lag spike for you? 

I'm going to focus on playing/rating the other submissions for now, but I do intend to continue working on this. Adding combat, a dozen more types of interactives (levers, buttons, pressure plates, etc.) and  sound...

I would have to replay to more specifically catalogue the places I noticed, but I do believe trying to use the key on the keyhole (clicking on it) seemed to freeze my cursor for a little bit.

I assume trying to load or instantiate something may have been an issue since it's pretty clear graphics aren't a problem.

interesting, that is not what I was anticipating. The only time during game play any objects are instantiated or destroyed are when an item is dropped/thrown with the right mouse button(instantiated) or a dropped item is picked up (destroyed) otherwise stuff is just moved around. The keyhole doesn't even actually destroy the key. it is just another container like the alcoves or sconces...