Not totally sure. I would first download a fresh version from Itch and extract into a folder. Then try to launch that new .exe. It could be your antivirus is blocking it? Maybe it had crashed or is still trying to load and you need to end the process in task manager. I assume you're on a laptop due to the small resolution and if you have a dedicated GPU make sure to enable it and disable your IGPU as it may have issues switching back and forth for this.
I'm not sure what you mean by 'this folder'. The main directory once you extract should look like this. If it's already gone from a fresh install than I'd assume one of your anti virus programs/firewall is automatically quarantining it. Otherwise, look in your task manger for "Growth RPG" and if you see one, end task it. Try launching the game again.