This is a really cool concept!
What you have here is a bit overwhelming to play however, My first thought is to reduce the amount of artifacts to correct and use the extra space to add more theming, stun guards, etc
A visual indicator of what is and isn't correct without having to check each box again would go a long way. Maybe once you've checked once it shows it on screen somehow?
The limited amount of artifacts you can carry is a good idea but I think it should be balanced with giving the player more information or places to put them, I noticed it was quite easy to get stuck holding artifacts with nowhere for them to go.
I think this could be a really cool game. Good luck if you decide to take it further!