I think that is the problem. Try running at half the resolution and zero text scaling just to see what it looks like. It is trying to scale it up to 4176 from 1920. My monitor runs at 2560 even though it could run at 5120. It only scales like +33% and looks good. Yours is doing +110%. I will try it at 5120 to see what it looks like.
No problem. I know you have a lot on your plate right now. I just used Nvidia control panel to adjust color settings and got a happy medium. Still not as good as your screenshots but better. The game looks decent. I saw in part 2 how the models got better as the game went on. High fidelity models are great. And when you have nice shadowing going on it shows more depth (3D) not DOF. I hate DOF. :)
Also, I would like all the models to look as stunning as this pic below which might warrant a remaster obviously. Just saying. :)
And a longer sex scene with this hybrid:
And sorry if I posted the pics on wrong game. :) Part 2 was /thumbs up. Keep up the hard work.