Hey there!
That sounds amazing! Personally I'd leave combat out of it entirely to increase the helplessness and fear of getting caught, as it's always scary being hunted by things you cannot harm or kill. You could have it so the students need to work together through the use of stealth and distractions (the jock distracts the creature while the nerds sneak on by)!
Amazing idea, bro. You have a superb imagination :)