I just installed FS-UAE v3.1.66 and v3.1.68 launcher on my Windows 10 machine.
All I did was select CD32 from the Amiga Model, the ISO file in the CD-ROM drive, and set Fast RAM to 4MB. It ran without problem. Took maybe a minute to get to the main menu though. You don't need a CUE file.
When you say it crashes, what happens? And what system are you running on?