Great game, the gameplay is really novel and addicting!
My setup:
Bounce bullets will pierce perk
Double Shot + Double Shot + Energy Refill + Next will Bounce + Bullets = # played + Next will Bounce = Literally cannot lose
Once you get your card drawing order as the above after each level, just spam the button E. The idea is to quickly cycle 0-cost cards to get to the important "clear screen" combo. Note not to take the Freeze spell to maximize the speed of game progression.
My computer was lagging in the end because the entire screen was covered by the Bullets = # played card, reached level 45 before I called it a quit.