Thanks for asking, short answer...
Possibly?
As it is, the stress and trauma rules stand in for old-school "Insanity" mechanics. Things like corruption weren't directly part of that old-school until much later, so if you are using a setting that has corruption, you can track that on the stress tracker and simply roll on a corruption table from that setting to determine if you gain physical corruption instead of the panic & mental trauma that is included with the current rules.
However, I am finishing up a campaign model (see draft below) that sets up the characters as bounty hunters in the old world. After that, I was thinking about a follow-up campaign model that would allow for more of a Call of Cthulhu vibe, I might try to include physical corruption as part of that. Have to think more if it's going to be a good fit.
It's not my goal to remake all of a certain product but rather to provide the tools to help make those worlds more accessible and empower GMs and Players with paired-down rules to fit any low fantasy world.
