From the rules, I would interpret that as no:
Use the same control limitations as the GameBoy (D-pad, A, B, select, start). These can be mapped any way you like.
Thank you for your answer! :D
I can confirm @marclurr's answer. You can't use the mouse as input, the inputs must match the limitations of the gameboy.
cool man danke habibi
kein bock mehr lol