I 100% agree with you that autism isn't something that should make people feel pity. But the jokes iirc, go something like:
1. The interface was designed for people with autism.
2. MC vehemently denies that he is autistic.
3. He is then told "sure buddy, whatever you say ;)"
Maybe it's all going over my head but, basically the punchline is "lol, you must be autistic!". Which is like, okay maybe they are, maybe they aren't, but is it supposed to funny (that someone is autistic)?
So where is the line? Do we not find fart jokes funny anymore? Fat jokes? Blonde jokes? Burnette jokes? Red head jokes? Religious jokes? Bully jokes? Work jokes?
The whole "its fine to laugh until someone makes fun of something I relate to" stance is just bad. Some jokes fall flat or are in bad taste, but getting overly hung up on them is kinda a huge reason why a lot of things suck these days. If you can't laugh and make fun of the shit you deal with, your life is gonna get depressing real quick.
