it’s a hint for the location of one of the rooms, where the bottle is. I think it’s on the floor of the managers room when you get access to that
Viewing post in Abby & Veleno in The Great Hotel Caper comments
Yes, that was my first guess when I saw the clue. I thought it said that I should go to the middle room in this floor, but when I finally got access to it, I found nothing in spite of my best efforts. The only hope I have now is to find a way to cross the hole in the third room on that floor, but then I do not understand why the clue says "Not the first and not the last"