No worries, thanks for the detailed feedback! There's a lot of things I want to change and fix so this gives me a good list of important stuff to start with.
One more thing actually - research doesn't seem to consume points. Not sure if it's a design feature :)
If you're still hunting for the masculine tf bug, the loop goes like this: the tf log reports every few hours that the subject has developed physically masculine traits, but the tf doesn't progress from there. I can't remember which genome the serum was based on.