Your art style has always been very colorful. It's beautifully done from the opening to the end. I think the narrative part is well thought out and has a well developed backstory. But in a way I as a player don't feel your narrative. My suggestion is that maybe besides talking to NPCs, you could add some NPC actions or trigger some extra events instead of just picking up stuff and taking medicine. Also how you balance your music material is important, players who are constantly startled by sudden sound effects may not be able to immerse themselves in the game.