How to avoid each character:
Milkamean: Close the door on the left. If she gets into your office and starts to force feed you burgers, shine your flashlight into her eyes.
Suki: Close the door on your right. If she gets into your office and begins to pump you full of air, match the corresponding buttons on the machine from her exhibit that is normally used to deflate her balloon.
Paranoia: If the phone rings, answer it. If the ads pop up on the computer, close them. Failure in doing so will lead to Paranoia attempting to escape the computer. If she tries to get out, shine your flashlight on her and hold until she goes away.
Elina: If her spectral hands show up on screen, shine your flashlight on them and they will retract.
Cindy: If you hear her wings flapping, hurry to the door on the left and close it quickly.
Cruxia: Click on her when you spot a black and red mass or figure in either the foyer or in one of the gift shops. You only have one hour to find her before she reaches your office.
Hana: She will attempt to enter your office from either the right or left door. Regardless of which one it is, close them. If she crosses the barrier, quickly knock the tray of burgers out of her hand.
Achira: Close the door on your right. If she gets in the office, there’s no getting her out. She will remain in there for the rest of the night. In earlier versions of the game, she doesn’t kill you, just makes you fatter and easier for the others to catch. In later updates, she kills you after you look away and look back three to four times while the white barrier is onscreen. To keep her gaze at bay, shine your flashlight at her.
Crystal: If you see her in the vent, close it immediately.
Thorne: Check when her stream starts (Depending on the night and its run, it will start within one or two hours). When the stream starts, be sure to click the heart icon several times to keep her happy. If you don’t click the heart enough times or you don’t click at all, she’ll think you’re ignoring her on purpose and begin to place a technical difficulties screen on each camera until she reaches your office.
Emily: If you see her in the hallway on the right or left, close the door immediately. If you see her in the vent, close it immediately.
Nougat: Listen for the pillars on the left side of the door. If you see the pillars, close it immediately. You only have a couple seconds to react before they cross the barrier and Nougat herself doesn’t move until the pillars reach your office.
The secret character: Seeing as how they have a rare chance of spawning, you won’t encounter her much. The few times you do, she will sit on your desk and smother you with her breasts if you stay in the office too long. I think to avoid her, leave the office, though I am not a hundred percent certain.
Senator Lyko: She appears when the power goes out. If you’re close to 6 AM, wait until the clock hits 6 AM. If you’re nowhere near 6 AM or she and the RNG aren’t feeling merciful, you’re pretty much screwed.