Hi! I haven't personally tested the game out with screen readers, but I wouldn't be surprised as 99% of the text is displayed as strings rather than graphics. These are very visual games, though they have been tested with various vision-impaired players to great success. However, if you are fully blind, it's unfortunately probably not a great fit. If you have at least some vision, there's a lot you can do in the game to improve your experience, such as turning off background images, reducing screenshake, and slowing the game speed.