Really cool concept! I like how you made the rare disease a main mechanic, while also adequately describing it and its treatments. A little feedback:
- The continue button after you beat level 2 takes you back to level 2 instead of to level 3. I thought you were reusing levels until I realized the button was broken.
- The puzzles are cool, but the use of enemies that move on their make it too hard to be enjoyed. It would be better if the enemies moved when the player moved, much like 'baba is you' or something like that. By doing this, the player has more control and does not feel like the game is screwing them over.
- The difficulty curve is pretty high. The first two levels mostly require focusing one one orb while making sure the others are not softlocked, then moving on to the next. After that, things got very complex, and with only two eyes yet four screens, it became overwhelming. I'd recommend starting with maybe just 2 'personalities,' then slowly scaling up to four so that the player does not get overwhelmed.
- The music is very quiet. I thought there was no noise at all until I read the description.
Besides these errors, it's a great game! The system has a lot of potential for more puzzles if you ever return to it.