So you give her the brooch (though it still remains in your key items afterward), come back and the window is dim and she's no longer there. Steps 1 and 2 done. But...now what? No body on the ground by the troll down the ladder, and the giant boar in the sewer drops nothing still. IIRC the door up the stairs in Iosefka's clinic "didn't open from this side" implying you can actually get to the other side of that. That's the only place I can think of where she might be, only because it's the spot she heads to in the actual game if you direct her there but I'm not sure it can be reached in this version (and would probably not make sense for her to appear there after this anyway). It's probable that the quest was altered here like a number of other things were altered here so... just, OK, where do I go now?