Hi,
I had issues with my 21;9 monitor, setting to resolution 2560 x 1080p caused the UI to scale off the screen within menus and the game, meaning I could not interact with the Ui at all.
Temp solution was to window the game (alt-enter), move the game onto my 16;9 monitor and set a more standard resolution.
I think it would be a good idea to have a fail safe default proceed button and back button allowing to interact even if it doesn't scale correctly.
-Also one of the analogy doors that leads to the next area will make the character stuck in place.