I keep encountering issues, enemies wont die, I can do hundreds of red dmg to them and nothing happens, even regular goblins. Is this a known bug? It's making some aspects of the game unplayable. 

Very likely caused by a cheat mod, as this bug did not appear in the base game.

If anyone encounter any major bug in the game, please feel free to ask in the community.  🙏 Much appreciated if you upload a screenshot, and a save file of the replicated bug preferably without mods, for quick troubleshooting.

Game version being used is also super important as there was that 1 version that was actually making everyone immortal. And the version before that one made everyone always have max willpower.