My game crashed twice now and I lost several hours of progress both times. I'm just waiting for the auto clicker to get me 100q at the moment with max upgrades so I just went back to the grind immidiately still it's really annoying to lose several hundred hearts and a few q soulstones.
edit:I decided to try to reload to save it just in case and that also didnt save it (there is enough disk space).

The game already does Auto Saves every five seconds.

If you had the tab open and still lost progress, that is weird. 

What browser are you using? 

What auto clicker are you using and with which settings, could it be that it causes a crash?

How exactly does it crash? Are there any errors in the browser developer console? (Ctrl + Shift + I on Chrome to open after clicking outside the game window.)

I used chrome. The game window had that 'error symbol' that often happens when things fail to load or crash without crashing the whole page or browser

The auto clicker doesnt have any special settings but its set at the fastest possible speed.

When I switched to firefox that I used before on a different computer without issue it didnt seem to crash even after a few hours but I havent closed it yet so I can't confirm if it saves.

Also on this computer I found that it went into 'idle mode' while using it on both chrome and firefox while auto clicking which might be a quirk of that specific computer but it might be worth noting.

The dev tools console on firefox says things about "[save_file] _write" and "[WORKAROUND] workers error" though Im not sure if that will help much I will try to replicate it on chrome when I have the time