The theme of the jam is A Stranger in a Strange Land
The protagonist must be in a place with a culture they are completely unfamiliar with, and the issues they face are a result of that unfamiliarity.
They could merely be in an isolated foreign country, or they could be from a different planet, dimension, time, etc than where the story is taking place. Simply being lost or somewhere they've never been is not enough, however. They must be in a culture they are unfamiliar with.
The unfamiliarity with the culture must be the main cause of their problems achieving whatever goal they are trying to achieve.
Have fun with the jam!