I’m glad you enjoyed the game and played so thoroughly into the postgame.
Needing to use the mouse after the engagement when your invisibility gets removed is not expected behavior, and if it’s happening, it’s a bug.
Did you use “Z” to confirm or “A” on the controller for dialogue windows? Besides clicking the buttons, those are the only two ways it should be closing.
As per the gameplay, the invisibility treasure you got I judged was too op. I loved the effect too much to nerf it, but still didn’t want it to just make the game too sneaky. The enemies you encountered, as well as the slime swarms were meant to counter it and make approaching each empty room a bit nerve wracking and not as easy as the early levels.
And as much as I’d like to have added a few more things (I originally wanted to make a dragon on the 10th floor with some special abilities for a secret ending, it would have had its own last stand and summon some minions when it last stood and fled) I barely got what I wanted done and spent the day I was expected to take off and relax fixing a few game breaking bugs that never showed up in my earlier tests.