Neat. ^^ And I would say there is never such a thing as 'lacking' only more of such a thing of not having the knowledge yet. We learn and improve and get better as life is a learning process. If you are that interested, you can do it, even if there are struggles as you learn the ins and outs of working with Renpy and other programs. If you decide to do it, I wish you the best of luck for it.
I don't know Renpy.
The animation would be done in 3D with Blender. That would mean making and rigging 3D models. And creating the small world environment for the events to take place in. After, I would need sound, and some form of voice over.
It would be a project, one I be only a little familiar with.