Man this was great! I wasn't quite able to figure it all out, but I want to go back and play some more of this later. My constructive feedback would be:
Pros:
Menu was awesome, I loved the effects and just how well it fit the game.
The concept is excellent. Funny, fun, engaging. Well done!
The controls themselves felt good.
Art was great, hilarious using the same faces.
Cons (just a little tweaking could easily fix):
It was a little hard to tell what options you had other than just attacking the guests. I didn't even know there were humans in the room until after attacking about 6-8 characters, since I would attack them and then they'd catch up to be and get me.
I have two monitors and during the game when the mouse disappeared it was still moving in the background. Every time it went to the second monitor I lost control of the game. I also had that happen with the menus, sometimes if I clicked next to the button the mouse would disappear making it hard to select something. Nit-picky, I know. haha.
Overall, I loved it. Well done!