I haven't gotten far in the game but the use button on items is not there. I physically can't use potions but I can use other things like the difficulty changer and the appearance and the cheat. but for potions and other key items I can't use it at all. I just beat the first dungeon so sorry if I seem confused but if you can how do I fix the issue because I don't want to create a new save or a new playthrough. sorry for the late reply I went on a trip.
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There basically aren't potions in the game, unless you are talking about the linking device. You should be able to use the linking device outside of combat, but not inside of it. If you let me know specifically what other items you are trying to use but can't I can check on them, but if you can use the difficulty changer and appearance items it sounds like things are working properly.