Thanks! For now the difficulty was set... intuitively; so the things you just find by exploring are easy, the ingredients that require some encounter, combat or more effort are medium, and the ones really hidden or hold by a creature are hard. Hope it makes sense, I guess that after more playstesting it can be adjusted.
Yes, the details on the map are quite small, also I think that the isometric maps are by nature harder to parse, since they have a 3rd dimention and verticality there is no clear path for the eye to follow. I tried to divide it by sectors to make it less overwhelming.