A game I very much enjoyed. I'm going to give critiques, because they may be of use to you, but don't take them too personally.
Writing - The writing is solid. Very relaxing dialogue that makes you smile. I appreciate the casual flirtation between the MC and Cynthia, it suits Cynthia's character. I think there were one or two jokes that I laughed aloud at.
I like theme of having the nature of Pokemon human-relationships contrasted by the player and the Kate. Amphy adds to this, with it being unprotected because it's not "owned" by Jasmine. As well as the haunted house Pokemon's backstory (trying to stay vague here to not spoil).
The Houndoom fight conclusion was very cool and the haunted factory part was great. Both were tense and made you think afterward.
Notably, the events of the game seem to have rather clever problemsolving, which belies writing talent.
I liked the plot, I liked the mystery, I liked the end of the game.
If there's one thing I can give advice on writingwise, it's premise. The game advertises itself with Cynthia. The only problem is, the coolest scenes in the game were the Kate part hunting for Houndoors, and the investigation of the haunted mill with Jasmine. See the problem? No Cynthia!
Now I hardly minded it because the scenes themself were excellent, but I think they would have done well to further develop the connection between the player and Cynthia, via the suspension bridge effect.
Um, this critique isn't urgent at all and may seem trivial, but I think works that revolve around fansa for a character should dump as much fansa as possible in the work, rather than getting distracted with side characters. This is up to you though, as I'd be remiss to say the side characters didn't have weight.
Art - The art direction is very inconsistent. You mix flat pokemon graphics with photo backgrounds and pixellated labels on the imagemaps. I'd recommend looking into consistency across the board in all these, because having a recognizable and pleasant style will draw more people in. Unfortunately, it's understandably difficult, either requiring a budget or a BG slave. But it will propel your game from looking like a Renpy test demo project to it's own visual novel with its own style.
I do think the sprites look very clean and attractive, and the photo backgrounds are also very pretty but the problem for me is they just... don't fit together.
Music - Pretty decent. I hardly noticed it.
UI - Generic Renpy UI is anathema on the eyes for people who have played a lot of Renpy games. If you're looking to make VNs in the future, I recommend updating the menus to literally anything else. Aside from that, the menus in the achievements and the background are fine.
I happened to think the pixelated black and white Pokemonesque labels in the imagemap look nice, and wondered what the game would look like if the textbox used that style.
But they contrast with the menus and the quickmenu, and the time counter, and the photo background. Needs to be less glaring contrast. Perhaps play with filters?
That said, I do see you using filters to make characters darker in darker scenes. I like that you do that, it's the little things that make it more atmospheric.
BGs - Aside from my complaints earlier about consistency, the BG choices are very good. They're consistent with each other and my vision of the town. I... may have used a couple of the same ones lol.
Transitions - It's alright. I like that you have the concierge behind hotel desk, it works well. But when he flips sprites, it happens a bit too quick. For this I recommend a dissolve transition to go along with your xzoom -1. You do this sometimes, but it's not consistent.
Additionally, wouldn't the pixellate dissolve for scene transitions work well for the Pokemon theming? Eh, it's up to you though.
Sizing - Weirdly noticeable. Everything is at several paces away. You change it up a little bit, but there's a lot of focus on keeping everything centered for some reason. There are points where you I wouldn't mind some scenes having characters get up close and personal, or start farther away.
For instance, in the scenes where you're sitting in a cafe or bar with Cynthia, it's still a standing sprite overlapping the table. If you were to zoom into the BG and Cynthia at shoulder level, it could have the appearance of her sitting on the couch without having to show the legs. Am I making sense? I feel like I'm not making sense.
This comes with its own downsides though, like not being to see the full BG. There's never a perfect solution.
Once again, I'd like to compliment your visual novel, and tell you not to take my critiques so seriously. I was been feeling melancholy this week, and this VN cheered me right up. Here's to your future projects! I can't wait to see them :)