I've gotten a chance to look at the final thoughts.
If the "black Tower Lord" is the Tower Lord I'm thinking of, that one's very hyper-focused on offense, but has some inherent "prep time" where he uses a certain move. Chilling him or speeding Brill up will probably help a lot; on the other hand, if you can land a Tinderspark+Quickburn on him, that alone can eat through a generous portion of his HP while you block his attacks. As for the "white Tower Lord", don't rely on Immunity potions and, if you have Wind potions, be ready to deflect his big attack (as he always has to "Prepare" it, which will reset deflect immunity).
The post-battle healing would be an interesting idea. Builds that rely on being at low HP might also benefit from an "HP to One" NPC in the first room. I'll think about it! Still figuring out the logistics of buyable research.