Interesting game entry with a fun theme.
I wasn't able to decipher any of the artwork or extract any clues to find more than 14 of the secrets.
The gameplay almost felt like a calculator that asks you to guess a random number within a range and could only tell you if you were right or wrong. When you finally get a right answer your reward is to try to guess within an exponentially larger range for the next one. After 14 I was tempted to calculate the number of possibilities but I am pretty certain that it may end up being more than the number of atoms in the universe. Some of the items combined intutively and unlocked a new secret, though many combinations that produce something in our known world had no effect in the game, so after a bit I just started mashing without a clue.
Shows lots of promise though, I could imagine all sorts of ways that clues could be revealed in the game or interesting reactions that could happen. I could imagine this being really fun too with the rhythm mechanic you were describing. Also I could imagine animations or art that gave some clues, or at least give a hint that you were on the right track. Overall Nice work!