Really cool game that's obviously had a lot of passion put into the art and gameplay. That being said, I agree with what paisleypug mentioned, and I want to also add that maybe rather than having tons of each enemy everywhere, maybe just concentrate on having 1 or 2 specific enemy types in specific areas (and maybe lock the player in rooms like you had mentioned on the stream) that way you have to figure out the various ways to beat each enemy type. As it is the enemies are kind of spread out and chaotic, which makes it better to just run through rather than fight them all at once.
However, this is still one of the most polished and deep games (gameplay-wise and artsyle-wise) in this jam, so congratulations on that!