Some tips from my side to deal with the difficulty:
- Play on easy. Trust me it's alreadey brutal.
- Don't skip the tutorial. You will start with 2 rather easy delivery orders which will allow an early upgrade for your ship.
- You're on a dilivery ship not a destroyer. In most cases running is the better option than fighting.
- Most enemies will not follow through worm holes. Only the Hunter type will track you through the whole galaxy after it sensed you.
- The same galaxy name will result in the same generated galaxy. So you can try to remember where the worm holes lead.