Great work on your first jam! Game is pretty basic right now, but if you put time in it, it can grow to something pretty nice. Liked the smoothness of your animations, even if you had little time for them.
Regarding optimization, game ran smoothly yet with a couple of bugs. Seems like you're planning on updating it, so 1) collecting honey after a death with having it doesn't display it; 2) collecting poison after that and ending the level crashes the game; 3) BGM slider didn't control music's volume.
General optimization tips : Optimization takes your precious jam time, decide if it is worth it; Some things do not need to be ran every frame, move them to creation or on event scripts; For something simple you do not need giant textures, if you're shrinking them to what you need anyway; On major steps check how your game runs on your to-be-exported-on platform; Know the limitations of that platform; Keep learning and look for help if you're stuck! (but look at the documentation first)