In the Radiative menu, it's at the very bottom.
Purchasing the core STAGE 2 LOREDs will unlock the Extra-normal upgrade menu again. Them being, Water, Seeds, Trees, Soil, Humus, Sand, Glass, Axes, Wood, Hardwood, Draw Plate, Wire, Liquid Iron, and Steel. Purchasing upgrades before you own any of these can potentially soft-lock the game forever. That's why I also added Radiatve upgrades to give you bonus Steel, Wire, Hardwood, and Glass after doing Chemotherapy