I really enjoy the visual style of this game! As an aside I think it would work great if you added ranged and mounted combat just because of the visual relationship of the sprites to the field of view.
Anyway I digress. The sound effects are effective and (I think?) the zombie sound effect was especially spooky.
The combat was difficult for me because I found it hard to target an attack instead of switching to a movement command, but it could be because my mouse is half broken it's mucking it up. Perhaps some kind of target reticule could appear when you're in combat mode. Also I'd suggest fixing the drop of the first spiderant so that you get some type of weapon, this would make the progression curve a little easier at first, but I could see how this might not be desired.
I'd certainly play more of this if you were to expand on it, good job.