Once ranged combat is included (a high priority) you will be able to shoot into arbitrary directions. In our opinion this even increases combat death as there will be a more notable difference between melee and ranged combat. Let#s wait for a final assessment until that arrives.
Interesting side fact: Many early test players totally did not miss diagonal movement, espescially since many people these days play on notebooks and there is just no really sane way to handle diagonal movement on a notebook (YMMV.