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In the latest release of the mac version the main menu appears blank except for the background, title, and a darker bar on the left side. When mousing over the darker bar on the left side, white lines appear as if your cursor was over an option but clicking doesn't do anything.

That sounds like the game is not having permission to get to the save file location. Try giving it permission to do that, on windows would be just running as administrator, not sure how it works on mac though