This is the closest I've felt to a traditional metroidvania yet, your game really captivates the metroidvania feeling!
Also, the alchemy theme is well integrated into the mechanichs, making it a 'crafting' system was a clever idea, specially when gold is one of the main components of the items!
I got to be honest about the art, it has not clicked with me. A part of me wants to like its simplicity and what you tried to do making it textured, but the other part doesn't really like it (this is just a personal opinion though).
I'd like to complain about the spikes too, most of the time they are fine, but some input about when they are going to fall would be gratly appreciated! This is a great entry in this jam, good job! 😁