Is the window backdrop moving in the main menu new or did I just never recognize that before? Its neat. But the moon seems to be way to high of a resolution compared to the rest.
Its 3D Now? Very nice, but the doorsprites shouldn't rotate.
Didn't play for that long, but the new mutations and book buffs feel very nice. Went all out on the science project or whatever with three times getting an extra radiation every 60 turns, the lifesteal thing and getting more melee damage per radiation I have. Got hard locked once I went randomly berserk right next to a guardian robot in the graveyard at night tho. Character tried to keep attacking it, but couldn't since its dormant and invulnerable at night, so just stood there not passing turns. and since I was berserk I couldn't pass those turns myself.
From what I've seen so far tho, nice update.