i don’t really see the point in 2-3 extra starting synergies
i’m pretty sure there’s an item for virtually every synergy, so if you’re desperate for one you can just grab a couple of that item
prime examples:
spyglass - tactician
heavy shackles - bulky
stick effigy - haunted
heart of the sea - aquatic
etc
runs are easy enough, there’s no reason to make them easier