This is a really cool idea, and a striking visual style!
The only thing holding this game back is the gameplay. It is unwieldy to control, and clashes with the visual style of the game.
Also, minor problem: the low contrast of the dark-blue hearts on black background makes it hard to tell how much health I still have left. Maybe consider removing the hearts outright when you lose HP?
But the game really has a lot of potential - An interactive painting, with a gallery that is also a video game! I think this game could become something great! 😄