I really liked this one. The ambience and the sheer amount of content just from one room is impressive. Also liked the choice of music and art style.
The puzzles were great and I didn't get stuck anywhere except in the beginning when I had trouble collecting those canisters (I tried to click on them and when that didn't work, gave up like an idiot. It was only later that I realized I had to use the material synthesizer itself to get them.) The in-game hint system was very helpful, I used it a couple of times to make sure I was on the right track. But overall I had fun figuring everything out.
The only thing that I'd suggest is to increase the speed of some of the animations like when you sit at the computer or open the air lock because you have to do that multiple times and it makes you feel a bit impatient. Also, having to click multiple times when doing anything with items from the inventory was a bit tiring. But I'm nit-picking here. This is a fantastic game and I enjoyed it a lot!