Uh, can you explain what's happening to you? I'd like to help you, but I don't know anything about your situation
No problem, although this would be a minor fix, a Quality of Life, because you CAN run the program (the game, the .exe), when the Smart Protect pops up, you just need to click on "More info" or something like that on the corner of the window and a button will appear saying "Execute anyway" or something like that, and the game will launch! (This method works with any other executables you might be having trouble with).
Hope this helps you!