Heyo, I can reliably get to the desert. Still haven't hit the winter area.
I'm finding I'm really struggling with the "monsters take multiple hits" thing now. It means my playstyle has changed from very methodical to quite a bit more frenetic. Before, I just had to make sure I'd hit something once, and there was a natural risk-reward relationship with thorns. You have one, it's hard to aim, but if you have many and you fail at aiming and get hit, you lose them all! (which always felt horrible, but it meant you tried to avoid it) So I didn't have to worry about where I need to go next, or the next bit of path, etc. (I pretty much never use any of the other weapons because they're slow, hard to aim effectively, and are usually dangerous to me. I really don't need _more_ hazards.)
But now all these things take multiple hits. The turrets (of all types, it seems) and the shai hulud (yellow worm that follows me), etc. Those taking multiple hits is brutal. I've killed them, but it never feels worth it. It's always a pain the butt, and a waste of seeds.
So it means my play style has moved much more towards checkpoints and rushing strategies. Which works, but it means I often look at multiple hit enemies as almost purely environmental hazards (i.e. something to be avoided) instead of enemies (i.e. something to be defeated)