I knew I was gonna enjoy this one when I saw that it had credits for "squelchy squirt" and "chainsaw sound"...
The art and general feel are to die for! Awesome! A lot of people already mentioned that well staged cinematic moment with the giant creature in the start, so I'll add to the list of cool things you've got going on here with having you walk past the hanging spider lady thing while just thinking that at some point you'll have to go up past that creepy thing, haha.
Some of the combat could use a little work I think. For example, the boss that was a big misty skull thing could really use some telegraphing where his pops out to bite you. Improvements to the movement, which I see some others have recommended, could also help with some of this wonkiness.
And, maybe this is just the designer in me making crap up, but I'd love to be able to hold the mouse button and have the chainsaw stay out sawing away.
Anyway, this one is super cool! Maybe my favorite vibe of any game I've played. I love it, squelchy squirt and all.